Article

Unappreciated Subcontinental Admixture in Europeans and European Americans: Implications for Genetic Epidemiology Studies

2022-11-29

Abstract excerpt

<h4>ABSTRACT</h4> European-ancestry populations are recognized as stratified but not as admixed, implying that residual confounding by locus-specific ancestry can affect studies of association, polygenic adaptation, and polygenic risk scores. We integrated individual-level genome-wide data from ~ 19,000 European-ancestry individuals across 79 European populations and five European American cohorts. We generated...

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Literature Corpus work: 222f0b97-d912-5313-a887-166e08adc3a8
DOI: 10.1101/2022.11.28.518227

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