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Article

Subcontinental genetic variation in the All of Us Research Program: Implications for biomedical research.

American journal of human genetics - 5 Jun 2025

Gouveia Mateus H, Meeks Karlijn A C, Borda Victor, Leal Thiago P, Kehdy Fernanda S G, Mogire Reagan, Doumatey Ayo P, Tarazona-Santos Eduardo, Kittles Rick A, Mata Ignacio F, O'Connor Timothy D, Adeyemo Adebowale A, Shriner Daniel, Rotimi Charles N

Abstract excerpt

The All of Us Research Program (All of Us) seeks to accelerate biomedical research and address the underrepresentation of minorities by recruiting over 1 million participants across the United States. A key question is how self-identification with discrete, predefined race and ethnicity categories compares to genetic variation at continental and subcontinental levels. To contextualize the genetic variation in All...

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Identifiers

PMID: 40480197
DOI: 10.1016/j.ajhg.2025.04.012
PMCID: PMC12256905

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