Article

Multicompartmentalized microvascularized tumor-on-a-chip to study tumor-stroma interactions and drug resistance in ovarian cancer

2024-06-02

Abstract excerpt

<h4>Introduction</h4> The majority of ovarian cancer (OC) patients receiving standard of care chemotherapy develop chemoresistance within 5 years. The tumor microenvironment (TME) is a dynamic and influential player in disease progression and therapeutic response. However, there is a lack of models that allow us to elucidate the compartmentalized nature of TME in a controllable, yet physiologically relevant manne...

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Literature Corpus work: 9d6bcf00-1977-5ea8-aa83-48702dd45095
DOI: 10.1101/2024.05.29.596456

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