Article

An <i>In Vitro</i> Vascularized Micro-Tumor Model of Human Colorectal Cancer Recapitulates <i>In Vivo</i> Drug Responses

2020-03-05

Abstract excerpt

Around 95% of anti-cancer drugs that show promise during preclinical study fail to gain FDA-approval for clinical use. This failure of the preclinical pipeline highlights the need for improved, physiologically-relevant in vitro models that can better serve as reliable drug-screening tools. The vascularized micro-tumor (VMT) is a novel three-dimensional model system that recapitulates the complex human tumor micro...

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Literature Corpus work: 0fb5574e-2523-5111-8ab5-c08c581a9b45
DOI: 10.1101/2020.03.03.973891

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