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Enhanced Efficacy of Low-dose Lovastatin through Probiotic-Mediated Absorption: Insights from In Vitro and In Vivo Studies

2024-01-17

Abstract excerpt

<h4>Background: </h4> Growing evidence highlights the crucial role of gut microbiota in drug metabolism, affecting both efficacy and toxicity. Probiotics, as part of the gut microbiota, possess a diverse array of enzymes and are likely involved in drug interactions. Our previous study demonstrated the ability of Lacticaseibacillus paracasei Zhang (LCZ), a probiotic strain, to metabolize lovastatin, a widely used l...

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Literature Corpus work
2197bb38-1440-5957-8f56-4d39693a4a43
DOI
10.21203/rs.3.rs-3864953/v1
Open publication

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Enhanced Efficacy of Low-dose Lovastatin through Probiotic-Mediated Absorption: Insights from In Vitro and In Vivo StudiesDOI 10.21203/rs.3.rs-3864953/v1
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