Development of a gut microbiota model for the analysis of bacterial modifications of xenobiotics

Abstract excerpt

<title>Abstract</title> <p>The human gut microbiota influences host physiology by metabolizing xenobiotics, such as drugs, dietary additives, and environmental contaminants. To enable standardized assessment of microbial xenobiotic metabolism, we established a defined bacterial colon model from pooled human fecal samples, by preparing clean bacterial cell suspensions using density gradient centrifugation. The bac...

Topics

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• Clostridium difficile and Clostridium perfringens research
• Diet and metabolism studies
• Effects and risks of endocrine disrupting chemicals
• Gut microbiota and health
• Metabolomics and Mass Spectrometry Studies
• Nutritional Studies and Diet
• Pharmacogenetics and Drug Metabolism
• Probiotics and Fermented Foods

Identifiers and source

Literature Corpus work

21fb1975-9184-568d-8bae-0838bb8852e0

DOI

10.21203/rs.3.rs-8136690/v1