Article

ORF48 is required for optimal lytic replication of Kaposi’s Sarcoma-Associated Herpesvirus

2024-02-29

Abstract excerpt

Kaposi’s sarcoma-associated herpesvirus (KSHV) establishes persistent infection in the host by encoding a vast network of proteins that aid immune evasion. One of these targeted innate immunity pathways is the cGAS-STING pathway, which inhibits the reactivation of KSHV from latency. Previously, we identified multiple cGAS/STING inhibitors encoded by KSHV, suggesting that the counteractions of this pathway by viral...

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Literature Corpus work: 63b751ae-130b-5617-bc83-c9c7d6a586f9
DOI: 10.1101/2024.02.29.582672

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