Article
A primary rodent triculture model to investigate the role of glia-neuron crosstalk in regulation of neuronal activity
2022-10-03
Abstract excerpt
Neuroinflammation and hyperexcitability have been implicated in the pathogenesis of neurodegenerative disease, and new models are required to investigate the cellular crosstalk involved in these processes. We developed an approach to generate a quantitative and reproducible triculture system that is suitable for pharmacological studies. While primary rodent cells were previously grown in a coculture medium formula...
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Identifiers and source
- Literature Corpus work
- 215f4d67-2b07-5314-9190-5e346bf9b841
- DOI
- 10.1101/2022.09.30.510271