Article

Vitamin D differentially modulates effector and regulatory T-cell migration across the blood-brain barrier

2025-12-12

Abstract excerpt

Multiple sclerosis (MS) is an inflammatory disease of the CNS influenced by a combination of genetic predisposition and environmental factors. Vitamin D (VitD) deficiency is considered a major risk factor for MS. While VitD is associated with immunomodulatory roles, the exact mechanisms by which VitD protects from disease are still largely unknown. CD4 T cells play a key role in MS pathogenesis with autoimmune eff...

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Literature Corpus work: 21411470-1440-5896-86b0-0fc1ad6f9f26
DOI: 10.64898/2025.12.09.692504

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