Article

Impaired suppressive effect of FoxP3 regulatory T cells on B cells in multiple sclerosis

2025-11-18

Abstract excerpt

<title>Abstract</title> <p> Background B cells are key contributors to the pathogenesis of many autoimmune diseases (AID), including multiple sclerosis (MS), and appear to evade the peripheral tolerance checkpoints that normally maintain immune homeostasis. The fate of B cells at these checkpoints is believed to be regulated by intracellular Ca <sup>2+</sup> signaling cascades triggered through engagement of B...

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Literature Corpus work: c70f4345-8581-5ab2-b23b-f15bbf6d8291
DOI: 10.21203/rs.3.rs-8039261/v1

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