Article

Pericytes regulate vascular immune homeostasis in the CNS

2019-05-20

Abstract excerpt

Brain endothelium possesses several organ-specific features collectively known as the blood-brain barrier (BBB). In addition, trafficking of immune cells in the healthy central nervous system (CNS) is tightly regulated by CNS vasculature. In CNS autoimmune diseases such as multiple sclerosis (MS), these homeostatic mechanisms are overcome by autoreactive lymphocyte entry into the CNS causing inflammatory demyelina...

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Literature Corpus work: 18d0367b-ea80-540a-9c2d-5e9ab5734a81
DOI: 10.1101/644120

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