Article
Targeted lipid A modification of <i>Shigella</i> vaccine strains reduced endotoxicity without compromising immunogenicity or invasiveness
2023-08-24
Abstract excerpt
Shigella infection contributes significantly to the global disease burden, especially affecting young children in developing countries. Currently, a vaccine against Shigella is unavailable and the prevalence of antibiotic resistance amongst Shigella species is continually rising. Live-attenuated Shigella vaccine candidates developed at Walter Reed Army Institute of Research have shown remarkable immunogenicity...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 213e58e1-8afc-5341-a320-8a565101324a
- DOI
- 10.1101/2023.08.24.554604