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Article

Lipopolysaccharide: a tool and target in enterobacterial vaccine development.

Biological chemistry - 1 May 2008

Nagy Gábor, Pál Tibor

Abstract excerpt

Lipopolysaccharide (LPS) is an essential component of Gram-negative bacteria. While mutants exhibiting truncated LPS molecules are usually over-attenuated, alternative approaches that affect the extent or timing of LPS expression, as well as its modification may establish the optimal balance for a live vaccine strain of sufficient attenuation and retained immunogenicity. On the other hand, a specific immune...

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Identifiers

PMID: 18953717
DOI: 10.1515/bc.2008.056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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