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Article

Toll-Like Receptor Activation by Generalized Modules for Membrane Antigens from Lipid A Mutants of Salmonella enterica Serovars Typhimurium and Enteritidis.

Clinical and vaccine immunology : CVI - 1 Apr 2016

Rossi Omar, Caboni Mariaelena, Negrea Aurel, Necchi Francesca, Alfini Renzo, Micoli Francesca, Saul Allan, MacLennan Calman A, Rondini Simona, Gerke Christiane

Abstract excerpt

Invasive nontyphoidal Salmonella (iNTS) disease is a neglected disease with high mortality in children and HIV-positive individuals in sub-Saharan Africa, caused primarily by Africa-specific strains of Salmonella enterica serovars Typhimurium and Enteritidis. A vaccine using GMMA (generalized modules for membrane antigens) fromS.Typhimurium andS.Enteritidis containing lipid A modifications to reduce potential in...

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Share to Africa South of the Sahara
Share to Antigens, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipid A

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Share to Salmonella enteritidis

Share to Salmonella typhimurium

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Source

Open in PubMed Open full text

Identifiers

PMID: 26865597
DOI: 10.1128/CVI.00023-16
PMCID: PMC4820502

Genes

TLR2
TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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