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Outer membrane vesicles derived from <i>Salmonella</i> Typhimurium can deliver <i>Shigella flexneri</i> 2a O-polysaccharide antigen to prevent lethal pulmonary infection in mice

2021-02-02

Abstract excerpt

The threat to health from shigellosis has become quite serious in many developing countries, causing severe diarrhea. Shigella flexneri 2a ( S. flexneri 2a) is the principal species responsible for this endemic disease. Although there have been multiple attempts to design a vaccine against Shigellosis, one that is effective has not yet been developed. Lipopolysaccharide (LPS) is both an essential virulence facto...

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Literature Corpus work
ff17d1e2-eb61-5598-a7f8-31415b0413f1
DOI
10.1101/2021.02.01.429291
Open publication

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Outer membrane vesicles derived from <i>Salmonella</i> Typhimurium can deliver <i>Shigella flexneri</i> 2a O-polysaccharide antigen to prevent lethal pulmonary infection in miceDOI 10.1101/2021.02.01.429291
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