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Exploring the Role of GMMA Components in the Immunogenicity of a 4-Valent Vaccine against Shigella

1 Feb 2023

Abstract excerpt

Shigellosis is the leading cause of diarrheal disease, especially in children of low- and middle-income countries, and is often associated with anti-microbial resistance. Currently, there are no licensed vaccines widely available against Shigella, but several candidates based on the O-antigen (OAg) portion of lipopolysaccharides are in development. We have proposed Generalized Modules for Membrane Antigens (GMMA)...

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PMID: 36769063
DOI: 10.3390/ijms24032742

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