Article

SGLT2 Inhibition Ameliorates Age-Dependent Renovascular Rarefaction

2025-06-28

Abstract excerpt

<h4>Introduction</h4> Aging is associated with progressive loss of renal function and vascular structure, with and without chronic kidney disease. However, the mechanisms driving renal vascular aging and potential therapeutic interventions remain poorly understood. <h4>Methods</h4> To model this state-of-affairs, we used African turquoise killifish (Nothobranchius furzeri), a naturally short-lived vertebrate. We...

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Literature Corpus work: 21269d8c-9bd8-5b93-ac02-5181a380d1ae
DOI: 10.1101/2025.06.27.654312

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