Article
Discontinuous transcription of ribosomal DNA in human cells
2019-09-16
Abstract excerpt
Numerous studies show that various genes in all kinds of organisms are transcribed discontinuously, i.e. in short bursts or pulses with periods of inactivity between them. But it remains unclear whether ribosomal DNA (rDNA), represented by multiple copies in every cell, is also expressed in such manner. In this work, we synchronized the pol I activity in the populations of tumour derived as well as normal human ce...
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Identifiers and source
- Literature Corpus work
- 20d3e69b-da37-5929-b08c-14ae2ed991b2
- DOI
- 10.1101/768929