Article

Phase separated ribosome nascent chain complexes paused in translation are capable to continue expression of proteins playing role in genotoxic stress response upon DNA damage

2022-03-16

Abstract excerpt

EDTA- and RNase-resistant ribonucleoprotein complexes of arrested ribosomes with protruding nascent polypeptide chains have recently been described in yeast and human cells. These complexes have been termed assemblysomes, a type of soluble condensates distinct from other known granules. Here, we use bioinformatics to identify additional proteins that likely form assemblysomes during translation. We characterize so...

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Literature Corpus work: eab608a3-48cc-52b2-a09d-00c6a744fcb6
DOI: 10.1101/2022.03.16.484567

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Phase separated ribosome nascent chain complexes paused in translation are capable to continue expression of proteins playing role in genotoxic stress response upon DNA damageDOI 10.1101/2022.03.16.484567Read

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