Article

Nek8445, a protein kinase required for microtubule regulation and cytokinesis in <i>Giardia lamblia</i>

2019-07-30

Abstract excerpt

Giardia has 198 Nek kinases whereas humans have only 11. Giardia has a complex microtubule cytoskeleton that includes eight flagella and several unique microtubule arrays that are utilized for parasite attachment and facilitation of rapid mitosis and cytokinesis. The need to regulate these structures may explain the parallel expansion of the number of Nek family kinases. Here we use live and fixed cell imaging to...

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Literature Corpus work: 20bf4fa4-77f5-5845-82e8-60ca59a5cd7e
DOI: 10.1101/719005

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