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Article

NIMA-related kinase TbNRKC is involved in basal body separation in Trypanosoma brucei.

Journal of cell science - 1 May 2006

Pradel Lydie C, Bonhivers Mélanie, Landrein Nicolas, Robinson Derrick R

Abstract excerpt

The NIMA-related kinase 2 (NEK 2) has important cell cycle functions related to centriole integrity and splitting. Trypanosoma brucei does not possess centrioles, however, cytokinesis is coupled to basal body separation events. Here we report the first functional characterisation of a T. brucei basal body-cytoskeletal NIMA-related kinase (NRK) protein, TbNRKC. The TbNRKC kinase domain has high amino acid identity...

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Source

Identifiers

PMID: 16608878
DOI: 10.1242/jcs.02900

Genes

NRK
NEK1
NEK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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