Article
Targeted single-cell RNA sequencing analysis reveals metabolic reprogramming and the ferroptosis-resistant state in hematologic malignancies.
Cell biochemistry and function - 1 Dec 2023
Shen Xiaohui, Dong Peiyuan, Kong Jingjing, Sun Nannan, Wang Fang, Sang Lina, Xu Yan, Zhang Mengmeng, Chen Xiaoli, Guo Rong, Wang Shuya, Lin Quande, Jiang Zhongxing, Xu Shan, Zhang Congli, Bian Zhilei, Wang Weimin, Guo Rongqun
Abstract excerpt
Hematologic malignancies are the most common hematopoietic diseases and a major public health concern. However, the mechanisms underlying myeloid tumors remain unknown owing to the intricate interplay between mutations and diverse clonal evolution patterns, as evidenced by the analysis of bulk cell-derived omics data. Several single-cell omics techniques have been used to characterize the hierarchies and altered...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.