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Article

Multi-omics analysis reveals glutathione metabolism-related immune suppression and constructs a prognostic model in lung adenocarcinoma

2 Jul 2025

Abstract excerpt

Background Metabolic reprogramming within the tumor microenvironment plays a pivotal role in tumor progression and therapeutic responses. Nevertheless, the relationship between aberrant glutathione (GSH) metabolism and the immune microenvironment in lung adenocarcinoma, as well as its clinical implications, remains unclear. Methods We leveraged genome-wide association study (GWAS) data and applied genetic causal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40672941
DOI: 10.3389/fimmu.2025.1608407

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