Article

Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human

2020-06-10

Abstract excerpt

<title>Abstract</title> <p>Receptor-mediated transcytosis (RMT) is a principal pathway for transport of macromolecules essential for brain function across the blood-brain barrier (BBB). Antibodies or peptide ligands which bind RMT receptors are often co-opted for brain delivery of biotherapeutics. Constitutively recycling transferrin receptor (TfR) is a prototype receptor utilized to shuttle therapeutic cargos ac...

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Literature Corpus work: 207f062b-f692-5337-9c2a-c9ba88849253
DOI: 10.21203/rs.3.rs-16449/v2

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