Article

A tissue-resolved endothelial surface proteome atlas informs organ-selective vascular targeting

2026-08-24

Abstract excerpt

BACKGROUND Endothelial cells (ECs) exhibit organ-specific functional diversity that shapes vascular homeostasis, disease susceptibility, and therapeutic accessibility. Although single-cell transcriptomic studies have defined endothelial heterogeneity at the RNA level, the in vivo cell-surface protein landscape that directly mediates vascular signaling and drug targeting remains incompletely characterized. Here, we...

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Literature Corpus work: 43178f81-973e-5c8f-912f-8c48e8f2ffd3
DOI: 10.64898/2026.08.21.746320

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