Back to search

Article

<i>Areca catechu</i> -(Betel-nut)-induced whole transcriptome changes associated with diabetes, obesity and metabolic syndrome in a human monocyte cell line

2020-08-03

Abstract excerpt

Betel-nut consumption is the fourth most common addictive habit globally and there is good evidence to link it with obesity, type 2 diabetes and the metabolic syndrome. We adopted a genome-wide transcriptomic approach in a human monocyte cell line incubated with arecoline and its nitrosated products to identify gene expression changes relevant to obesity, type 2 diabetes and the metabolic syndrome. The THP1 monocy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
205d80a5-a3f1-5b65-a7a8-80bb6ecc1819
DOI
10.1101/2020.08.03.233932
Open publication

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
<i>Areca catechu</i> -(Betel-nut)-induced whole transcriptome changes associated with diabetes, obesity and metabolic syndrome in a human monocyte cell lineDOI 10.1101/2020.08.03.233932
A pilot study evaluating genetic alterations that drive tobacco- and betel quid-associated oral cancer in Northeast India.Semantic proximity
Adverse Health Effects of Betel Quid and the Risk of Oral and Pharyngeal CancersSemantic proximity
Can transcriptomics provide insight into the chemopreventive mechanisms of complex mixtures of phytochemicals in humans?Semantic proximity
Betel quid-associated cancer: Prevention strategies and targeted treatment.Semantic proximity
Dietary nitrate intake and net nitrite-generating capacity of the oral microbiome interact to enhance cardiometabolic health: Results from the Oral Infections Glucose Intolerance and Insulin Resistance Study (ORIGINS)Semantic proximity
Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokersSemantic proximity
Downregulation of Ches1 and other novel genes in oral cancer cells chronically exposed to areca nut extract.Semantic proximity
Genetic toxicology and toxicokinetics of arecoline and related areca nut compounds: an updated review.Semantic proximity
Genetic Susceptibility and Protein Expression of Extracellular Matrix Turnover-Related Genes in Oral Submucous Fibrosis.Semantic proximity
Quercetin supplementation and its effect on human monocyte gene expression profiles in vivo.Semantic proximity
Carcinogenic Effects of Areca Nut and Its Metabolites: A Review of the Experimental EvidenceSemantic proximity
Fibrotic Effects of Arecoline<i>N</i>-Oxide in Oral Potentially Malignant DisordersSemantic proximity
Select a neighboring publication to make it the new centre.