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Article

Can transcriptomics provide insight into the chemopreventive mechanisms of complex mixtures of phytochemicals in humans?

Antioxidants & redox signaling - 10 May 2014

van Breda Simone G J, Wilms Lonneke C, Gaj Stan, Jennen Danyel G J, Briedé Jacob J, Helsper Johannes P, Kleinjans Jos C S, de Kok Theo M C M

Abstract excerpt

Blueberries contain relatively large amounts of different phytochemicals, which are suggested to have chemopreventive properties, but little information is available on the underlying molecular modes of action. This study investigates whole genome gene expression changes in lymphocytes of 143 humans after a 4-week blueberry-apple juice dietary intervention. Differentially expressed genes and genes correlating...

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Identifiers

PMID: 24328558
DOI: 10.1089/ars.2013.5528
PMCID: PMC3994912

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