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Article

Genetic toxicology and toxicokinetics of arecoline and related areca nut compounds: an updated review.

Archives of toxicology - 1 Feb 2021

Oliveira Nuno G, Ramos Daniela L, Dinis-Oliveira Ricardo Jorge

Abstract excerpt

Areca nut (AN) is consumed by more than 600 million of individuals, particularly in some regions of South Asia, East Africa, and tropical Pacific, being classified as carcinogenic to humans. The most popular way of exposure consists of chewing a mixture of AN with betel leaf, slaked lime, and other ingredients that may also contain tobacco named betel quid (BQ). Arecoline is the principal active compound of AN,...

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PMID: 33097969
DOI: 10.1007/s00204-020-02926-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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