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Article

Toll-like receptor 4 activation on human amniotic epithelial cells is a risk factor for pregnancy loss

1 Jan 2019

Abstract excerpt

Background: Maternal–fetal tolerance plays a fundamental role in the maintenance of pregnancy. However, this immunological tolerance can be influenced by intrauterine infections. Human amniotic epithelial cells (hAECs) have immunomodulatory effects and respond to invading pathogens through expressing various toll-like receptors (TLRs). We hypothesize that bacteria or bacterial products affect the...

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Share to Immune Response and Inflammation
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PMID: 30815014
DOI: 10.4103/jrms.jrms_463_18

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