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Article

Immunosuppressive potential of human amnion epithelial cells in the treatment of experimental autoimmune encephalomyelitis.

Journal of neuroinflammation - 3 Jun 2015

McDonald Courtney A, Payne Natalie L, Sun Guizhi, Moussa Leon, Siatskas Christopher, Lim Rebecca, Wallace Euan M, Jenkin Graham, Bernard Claude C A

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system (CNS). In recent years, it has been found that cells such as human amnion epithelial cells (hAECs) have the ability to modulate immune responses in vitro and in vivo and can differentiate into multiple cell lineages. Accordingly, we investigated the immunoregulatory effects of hAECs as a potential therapy in an...

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Source

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Identifiers

PMID: 26036872
DOI: 10.1186/s12974-015-0322-8
PMCID: PMC4457975

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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