Article

CombDNF: Disease-specific drug combination predictions with network-based features on clinically validated data

2025-02-23

Abstract excerpt

Drug combinations are increasingly applied to treat a wide range of complex diseases. Drug action and thus also drug combination effects can differ between diseases, e.g., due to molecular differences. Therefore, disease-specific predictions are required for treatments. A plethora of methods based on cell-line screening data in cancer has been proposed. However, their extendability to other diseases is limited, as...

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Literature Corpus work: 2038f672-c68e-5d3f-9dc2-603b86966c00
DOI: 10.1101/2025.02.18.637825

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