Article

Whole exome sequencing and gene expression analysis of canine osteosarcomas identify mutant TP53 and enriched immune pathways associated with longer survival

2021-01-12

Abstract excerpt

<title>Abstract</title> Osteosarcoma affects about 2.8% of dogs with cancer, with a one-year survival rate of approximately 45%. The purpose of this study was to characterize the mutation and expression profiles of canine osteosarcoma associated with outcome in samples from dogs treated by amputation and chemotherapy. The number of somatic variants identified across 26 samples ranged from 145 to 2,697 with top...

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Literature Corpus work: 202b87c8-fccb-533e-a452-eb6dd0e75e7e
DOI: 10.21203/rs.3.rs-135094/v1

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Whole exome sequencing and gene expression analysis of canine osteosarcomas identify mutant TP53 and enriched immune pathways associated with longer survivalDOI 10.21203/rs.3.rs-135094/v1Read

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