Article

Development of an exosomal gene signature to detect residual disease in dogs with osteosarcoma using a novel xenograft platform and machine learning

2021-02-12

Abstract excerpt

Osteosarcoma has a guarded prognosis. A major hurdle in developing more effective osteosarcoma therapies is the lack of disease-specific biomarkers to predict risk, prognosis, or therapeutic response. Exosomes are secreted extracellular microvesicles emerging as powerful diagnostic tools. However, their clinical application is precluded by challenges in identifying disease-associated cargo from the vastly larger b...

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Literature Corpus work: 8c5ac806-7fe5-594d-9212-c1cb14c2efdd
DOI: 10.1101/2021.02.11.429432

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