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Article

Expression profiling in canine osteosarcoma: identification of biomarkers and pathways associated with outcome

22 Sept 2010

Abstract excerpt

BACKGROUND: Osteosarcoma (OSA) spontaneously arises in the appendicular skeleton of large breed dogs and shares many physiological and molecular biological characteristics with human OSA. The standard treatment for OSA in both species is amputation or limb-sparing surgery, followed by chemotherapy. Unfortunately, OSA is an aggressive cancer with a high metastatic rate. Characterization of OSA with regard to its...

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PMID: 20860831
DOI: 10.1186/1471-2407-10-506

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