Article

Single-cell RNA sequencing reveals the cellular and molecular heterogeneity of treatment-naïve primary osteosarcoma in dogs

2023-08-09

Abstract excerpt

<title>Abstract</title> <p>Osteosarcoma (OS) is a heterogeneous, aggressive malignancy of the bone that disproportionally affects children and adolescents. Therapeutic interventions for OS are limited, which is in part due to the complex tumor microenvironment (TME) that has proven to be refractory to immunotherapies. Thus, there is a need to better define the complexity of the OS TME. To address this need, we us...

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Literature Corpus work: 1f38983a-7e61-59e0-8fae-7866ad1b8862
DOI: 10.21203/rs.3.rs-3232360/v1

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