Article

SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis

2024-03-25

Abstract excerpt

<h4>ABSTRACT</h4> RNA binding proteins (RBPs) containing intrinsically disordered regions (IDRs) are present in diverse molecular complexes where they function as dynamic regulators. Their characteristics promote liquid-liquid phase separation (LLPS) and the formation of membraneless organelles such as stress granules and nucleoli. IDR-RBPs are particularly relevant in the nervous system and their dysfunction is...

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Literature Corpus work: 1fe51525-1539-5189-b5d6-a68509652e5a
DOI: 10.1101/2024.03.22.586270

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