Article

Optimization of an adeno-associated viral vector for epidermal keratinocytes <i>in vitro</i> and <i>in vivo</i>

2024-04-19

Abstract excerpt

<h4>Background: </h4> Local gene therapies, including in vivo genome editing, are highly anticipated for the treatment of genetic diseases in skin, especially the epidermis. While the adeno-associated virus (AAV) is a potent vector for in vivo gene delivery, the lack of efficient gene delivery methods has limited its clinical applications. <h4>Objective:</h4> To optimize the AAV gene delivery system with higher ge...

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Literature Corpus work: 1fbfc13d-1298-5e84-b561-5a5ac27af044
DOI: 10.1101/2024.04.15.589645

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