Article

Optimization of human papillomavirus-based pseudovirus techniques for efficient gene transfer

2020-05-01

Abstract excerpt

Human papillomavirus (HPV) L1 and L2 capsid proteins self-assemble into virions capable of efficiently packaging either its 8 kilobase genome or non-viral DNA. The ability of HPV capsids to package non-viral DNA makes these a useful tool for delivering plasmids to study proteins of interest in a variety of cell types. We describe optimization of current methods and present new protocols for using HPV capsids to de...

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Literature Corpus work: 0a855d7b-50a2-54a8-afc3-59d1c4685892
DOI: 10.1101/2020.04.30.070573

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