Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Research Techniques Made Simple: Delivery of the CRISPR/Cas9 Components into Epidermal Cells.

The Journal of investigative dermatology - 1 Jun 2021

Shi Huishan, Smits Jos P H, van den Bogaard Ellen H, Brewer Matthew G

Abstract excerpt

CRISPR/Cas9 technology is a powerful tool used to alter the genetic landscape of various hosts. This has been exemplified by its success in the transgenic animal world where it has been utilized to develop novel mouse lines modeling numerous disease states. The technology has helped to develop both in vitro and in vivo systems that simulate diseases within the fields of epithelial biology, skin cancer biology,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to CRISPR-Cas Systems

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Transfer Techniques

Share to Genetic Vectors

Share to Keratinocytes

Share to Primary Cell Culture

Share to RNA, Guide, CRISPR-Cas Systems

Share to Skin Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 34024338
DOI: 10.1016/j.jid.2021.01.008
PMCID: PMC8224101

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Research Techniques Made Simple: Delivery of the CRISPR/Cas9 Components into Epidermal Cells.PMID 34024338Read ↗

Gene editing in dermatology: Harnessing CRISPR for the treatment of cutaneous diseaseSemantic proximity Read ↗

Research Techniques Made Simple: CRISPR Genetic Screens.Semantic proximity Read ↗

Challenges of Gene Editing Therapies for Genodermatoses.Semantic proximity Read ↗

Efficient in vivo gene editing using ribonucleoproteins in skin stem cells of recessive dystrophic epidermolysis bullosa mouse model.Semantic proximity Read ↗

Generation and characterization of CRISPR-Cas9-Mediated <i>XPC</i> Gene Knockout in Human Skin CellsSemantic proximity Read ↗

In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity.Semantic proximity Read ↗

Mammalian skin cell biology: At the interface between laboratory and clinicSemantic proximity Read ↗

Predictable CRISPR/Cas9-Mediated COL7A1 Reframing for Dystrophic Epidermolysis Bullosa.Semantic proximity Read ↗

Allele-specific CRISPR-Cas9 editing of dominant epidermolysis bullosa simplex in human epidermal stem cells.Semantic proximity Read ↗

COL7A1 Editing via CRISPR/Cas9 in Recessive Dystrophic Epidermolysis Bullosa.Semantic proximity Read ↗

Exploiting Mouse Models to Study Ras-Induced Cutaneous Squamous Cell Carcinoma.Semantic proximity Read ↗

Development of an Intrinsic Skin Sensor for Blood Glucose Level with CRISPR-mediated Genome Editing in Epidermal Stem CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.