Article

Amelioration of muscular dystrophy phenotype in mdx mice by inhibition of Flt1

2019-04-15

Abstract excerpt

Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disease in which the dystrophin coding for a membrane stabilizing protein is mutated. Recently, the vasculature has also shown to be perturbed in DMD and DMD model mdx mice. Data-mining DMD transcriptomics revealed the defects were correlated to a vascular endothelial growth factor (VEGF) signaling pathway. To reveal the relationship between DMD a...

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Literature Corpus work: 1f6428e5-c4a2-55a2-8c84-2bc36201640e
DOI: 10.1101/609735

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