Article

Devising reliable and accurate epigenetic predictors: choosing the optimal computational solution

2023-10-17

Abstract excerpt

Illumina DNA methylation arrays are frequently used for the discovery of methylation signatures associated with aging and disease. One of the major hurdles to overcome when training trait prediction models is the high dimensionality of the data, with the number of features (CpGs) greatly exceeding the typical number of samples assessed. In addition, most large-scale DNA methylation-based studies do not include rep...

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Literature Corpus work: 1f35ed07-0121-537e-88b3-b9b476735f25
DOI: 10.1101/2023.10.13.562187

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