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Article

Chronological age prediction based on DNA methylation: Massive parallel sequencing and random forest regression.

Forensic science international. Genetics - 1 Nov 2017

Naue Jana, Hoefsloot Huub C J, Mook Olaf R F, Rijlaarsdam-Hoekstra Laura, van der Zwalm Marloes C H, Henneman Peter, Kloosterman Ate D, Verschure Pernette J

Abstract excerpt

The use of DNA methylation (DNAm) to obtain additional information in forensic investigations showed to be a promising and increasing field of interest. Prediction of the chronological age based on age-dependent changes in the DNAm of specific CpG sites within the genome is one such potential application. Here we present an age-prediction tool for whole blood based on massive parallel sequencing (MPS) and a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28841467
DOI: 10.1016/j.fsigen.2017.07.015

Genes

KLF14
ELOVL2
GRM2
LDB2
SAMD10
TRIM59
DDO
HOXC4
MEIS1
NKIRAS2
RPA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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