Article

Dopamine-dependent cerebellar dysfunction enhances beta oscillations and disrupts motor learning in a multiarea model

2023-07-19

Abstract excerpt

Parkinson’s disease (PD) is a chronic degenerative disorder of the central nervous system that affects the motor system. The discovery that PD motor symptoms result from the death of dopaminergic cells in the substantia nigra led to focus most of PD research on the basal ganglia. However, recent findings point to an active involvement of the cerebellum in PD. Here, we have developed a multiscale computational mode...

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Literature Corpus work: 1ecfe88c-3eab-5c22-9634-ba159a135228
DOI: 10.1101/2023.07.18.549459

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