Article
Deep learning links localized digital pathology phenotypes with transcriptional subtype and patient outcome in glioblastoma.
GigaScience - 2 Jan 2024
Roetzer-Pejrimovsky Thomas, Nenning Karl-Heinz, Kiesel Barbara, Klughammer Johanna, Rajchl Martin, Baumann Bernhard, Langs Georg, Woehrer Adelheid
Abstract excerpt
BACKGROUND: Deep learning has revolutionized medical image analysis in cancer pathology, where it had a substantial clinical impact by supporting the diagnosis and prognostic rating of cancer. Among the first available digital resources in the field of brain cancer is glioblastoma, the most common and fatal brain cancer. At the histologic level, glioblastoma is characterized by abundant phenotypic variability...
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