Back to search

Article

Decrease and impaired function of circulating mucosa-associated invariant T cells in acute myeloid leukemia

2024-03-28

Abstract excerpt

<title>Abstract</title> <p>Acute myeloid leukemia (AML) is an aggressive cancer characterized by significantly low mucosa-associated invariant T (MAIT) cells. Though the reasons for their decline and their functional implications in AML are yet to be explored, their levels have been reported to be associated with the prognosis of the disease. This study aimed to characterize the frequency, phenotype, and function...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1eba595f-54c3-5f2c-ba37-3940981a32a1
DOI
10.21203/rs.3.rs-4017372/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Decrease and impaired function of circulating mucosa-associated invariant T cells in acute myeloid leukemiaDOI 10.21203/rs.3.rs-4017372/v1
MAIT cells numbers and frequencies in patients with acute myeloid leukemia at diagnosis: association with cytogenetic profile and gene mutations.Semantic proximity
High percentage of bone marrow CD8+ tissue-resident-like T cells predicts inferior survival in patients with acute myeloid leukemiaSemantic proximity
Increased TIGIT expressing NK cells with dysfunctional phenotype in AML patients correlated with poor prognosis.Semantic proximity
CD8+T cells expressing both PD-1 and TIGIT but not CD226 are dysfunctional in acute myeloid leukemia (AML) patients.Semantic proximity
A New Risk Score System for Early Warning Gastrointestinal Graft-Versus-Host Disease Based on the Immune Function of Mucosal-Associated Invariant T CellsSemantic proximity
mucosal-associated invariant T cells predict increased acute graft-versus-host-disease incidence in patients receiving allogeneic hematopoietic stem cell transplantation.Semantic proximity
Tim-3 is highly expressed in T cells in acute myeloid leukemia and associated with clinicopathological prognostic stratification.Semantic proximity
The profile and prognostic significance of bone marrow T-cell differentiation subsets in adult AML at diagnosis.Semantic proximity
Eomes+T-betlow CD8+ T Cells Are Functionally Impaired and Are Associated with Poor Clinical Outcome in Patients with Acute Myeloid LeukemiaSemantic proximity
Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts.Semantic proximity
The role of exhausted natural killer cells in the immunopathogenesis and treatment of leukemia.Semantic proximity
Exhaustion in tumor-infiltrating Mucosal-Associated Invariant T (MAIT) cells from colon cancer patients.Semantic proximity
Select a neighboring publication to make it the new centre.