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Article

MAIT cells numbers and frequencies in patients with acute myeloid leukemia at diagnosis: association with cytogenetic profile and gene mutations.

Cancer immunology, immunotherapy : CII - 1 Apr 2022

Comont Thibault, Nicolau-Travers Marie-Laure, Bertoli Sarah, Recher Christian, Vergez Francois, Treiner Emmanuel

Abstract excerpt

Harnessing or monitoring immune cells is actually a major topic in pre-clinical and clinical studies in acute myeloid leukemia (AML). Mucosal-Associated Invariant T cells (MAIT) constitute one of the largest subset of innate-like, cytotoxic T cell subsets in humans. Despite some papers suggesting a role for MAIT cells in cancer, their specific involvement remains unclear, especially in myeloid malignancies. This...

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Identifiers

PMID: 34477901
DOI: 10.1007/s00262-021-03037-9
PMCID: PMC10991316

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