Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The profile and prognostic significance of bone marrow T-cell differentiation subsets in adult AML at diagnosis.

Frontiers in immunology - 1 Jan 2024

Sun Kai, Shi Zong-Yan, Wang Ya-Zhe, Xie Dai-Hong, Liu Yan-Rong, Jiang Qian, Jiang Hao, Huang Xiao-Jun, Qin Ya-Zhen

Abstract excerpt

Background: T lymphocytes in tumor microenvironment play a pivotal role in the anti-tumor immunity, and the memory of T cells contributes to the long-term protection against tumor antigens. Compared to solid tumors, studies focusing on the T-cell differentiation in the acute myeloid leukemia (AML) bone marrow (BM) microenvironment remain limited. Patients and methods: Fresh BM specimens collected from 103 adult...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4-Positive T-Lymphocytes
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to DNA Methyltransferase 3A

Share to Leukemia, Myeloid, Acute

Share to Prognosis

Share to T-Lymphocyte Subsets

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 39100667
DOI: 10.3389/fimmu.2024.1418792
PMCID: PMC11294180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The profile and prognostic significance of bone marrow T-cell differentiation subsets in adult AML at diagnosis.PMID 39100667Read ↗

High percentage of bone marrow CD8+ tissue-resident-like T cells predicts inferior survival in patients with acute myeloid leukemiaSemantic proximity Read ↗

Single-cell map of diverse immune phenotypes in the acute myeloid leukemia microenvironmentSemantic proximity Read ↗

Immune-based subgroups uncover diverse tumor immunogenicity and implications for prognosis and precision therapy in acute myeloid leukemia.Semantic proximity Read ↗

Bone marrow tumor microenvironment profiling predicts distinct immunosuppressive phenotypes and immunotherapy potential in AML patientsSemantic proximity Read ↗

The interaction between common genetic mutations in AML and the immune landscape: mechanisms and implications for immune responseSemantic proximity Read ↗

Signatures of CD8+ T cell dysfunction in AML patients and their reversibility with response to chemotherapySemantic proximity Read ↗

Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts.Semantic proximity Read ↗

Clinical and Biological Implications of Mutational Spectrum in Acute Myeloid Leukemia of FAB Subtypes M0 and M1.Semantic proximity Read ↗

The Black Hole: CAR T cell Therapy in AMLSemantic proximity Read ↗

The Black Hole: CAR T Cell Therapy in AMLSemantic proximity Read ↗

Genetic mutations and immune microenvironment: unveiling the connection to AML prognosis.Semantic proximity Read ↗

CD8+T cells expressing both PD-1 and TIGIT but not CD226 are dysfunctional in acute myeloid leukemia (AML) patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.