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Analysis of the off-target interaction of amyloid PET tracers with human brain sulfotransferases

2026-06-21

Abstract excerpt

Positron emission tomography (PET) tracers targeting amyloid-β (Aβ) are central to the diagnosis and staging of Alzheimer’s disease (AD). However, growing evidence indicates that these tracers can engage off-target molecules, complicating signal interpretation. Sulfotransferases (SULTs) have been experimentally identified as binding partners of 11 C-Pittsburgh Compound-B (PiB). However, whether the clinically use...

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Literature Corpus work
1eb404cf-4d7e-5d45-a6d3-34bf203eaa28
DOI
10.64898/2026.06.16.732640
Open publication

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Analysis of the off-target interaction of amyloid PET tracers with human brain sulfotransferasesDOI 10.64898/2026.06.16.732640
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