Article

Genome-wide study of longitudinal brain imaging measures of multiple sclerosis progression across six clinical trials

2023-03-27

Abstract excerpt

While the genetics of MS risk susceptibility are well-described, the genetics of disease progression remain elusive. We therefore investigated the genetic determinants of MS progression on longitudinal brain MRI: change in brain volume (BV); and change in T2 lesion volume (T2LV), reflecting progressive tissue loss and increasing disease burden, respectively. We performed genome-wide association studies of change i...

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Literature Corpus work: 1e714044-a4c7-5e16-be50-61b65e48ff02
DOI: 10.21203/rs.3.rs-2666311/v1

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