Article

Epistasis lowers the genetic barrier to SARS-CoV-2 neutralizing antibody escape

2022-08-19

Abstract excerpt

Consecutive waves of SARS-CoV-2 infection have been driven in part by the repeated emergence of variants with mutations that confer resistance to neutralizing antibodies Nevertheless, prolonged or repeated antigen exposure generates diverse memory B-cells that can produce affinity matured receptor binding domain (RBD)-specific antibodies that likely contribute to ongoing protection against severe disease. To deter...

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Literature Corpus work: 1e669bca-02c4-5d19-9c71-5c6ff06cc5db
DOI: 10.1101/2022.08.17.504313

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